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CYP3A4 (e.g., Ketoconazole) — Ketoconazole (400 mg daily), a selective and potent inhibitor of CYP3A4, increased tadalafil 20 mg single-dose exposure (AUC) by 312% and Cmax by 22%, relative to the values for tadalafil 20 mg alone. Ketoconazole (200 mg daily) increased tadalafil 10-mg single-dose exposure (AUC) by 107% and Cmax by 15%, relative to the values for tadalafil 10 mg alone [see Dosage and Administration (2.7)].Use in Specific Populations

You should not take Cialis if you are allergic to tadalafil, or: generic cialis no prescription Figure 6: Mean IPSS Changes in BPH Patients by Visit in Study K Stress - for example, due to a difficult work or home situation.Sildenafil is available on NHS prescription for all men who have erectile dysfunction.

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